Functional state of mitochondria in chronic respiratory diseases

نویسندگان

چکیده

Introduction. Chronic respiratory diseases are one of the most common types non-communicable and an important problem our time. The induction oxidative stress, chronic inflammation hypoxia, which underlie pathogenesis bronchopulmonary system, can be determined at cellular molecular level by impaired mitochondrial functioning. Aim. This review is devoted to prospects for assessing functional state mitochondria as a fine indicator course diseases. Results. data domestic foreign sources on parameters functioning in normal pathology were analyzed. It has been shown that highly sensitive changes both exogenous endogenous homeostasis. Functional mitochondria, reactive oxygen species, membrane potential, fatty acid composition membranes used diagnostic prognostic criteria presented indicate need further studies pathology.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cytokines in chronic respiratory diseases

Cytokines are small, secreted proteins that control immune responses. Within the lung, they can control host responses to injuries or infection, resulting in clearance of the insult, repair of lung tissue, and return to homeostasis. Problems can arise when this response is over exuberant and/or cytokine production becomes dysregulated. In such cases, chronic and repeated inflammatory reactions ...

متن کامل

Resting-state Functional Connectivity During Controlled Respiratory Cycles Using Functional Magnetic Resonance Imaging

Introduction: This study aimed to assess the effect of controlled mouth breathing during the resting state using functional magnetic resonance imaging (fMRI). Methods: Eleven subjects participated in this experiment in which the controlled “Nose” and “Mouth” breathings of 6 s respiratory cycle were performed with a visual cue at 3T MRI. Voxel-wise seed-to-voxel maps and whole-brain region of i...

متن کامل

Screening for chronic respiratory diseases in Georgia.

Chronic respiratory diseases are an important cause of morbidity and mortality worldwide. Tuberculosis is responsible for 2 million deaths annually, COPD for another 3 million with an ever increasing trend. It is estimated that COPD will be the third most important cause of all deaths in 2020 and the fifth most important cause of DALY’s. COPD, asthma and chronic rhinitis are important causes of...

متن کامل

Respiratory Viral Infections in Chronic Lung Diseases.

Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis (CF) and interstitial lung diseases (ILD), affect many individuals worldwide. Patients with these chronic lung diseases are susceptible to respiratory lung infections and some of these viral infections can contribute to disease pathogenesis. This review highlights the associations of lung infect...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: ????????? ?????????? ? ????????? ???????

سال: 2022

ISSN: ['1998-5029']

DOI: https://doi.org/10.36604/1998-5029-2022-84-116-126