Functional state of mitochondria in chronic respiratory diseases
نویسندگان
چکیده
Introduction. Chronic respiratory diseases are one of the most common types non-communicable and an important problem our time. The induction oxidative stress, chronic inflammation hypoxia, which underlie pathogenesis bronchopulmonary system, can be determined at cellular molecular level by impaired mitochondrial functioning. Aim. This review is devoted to prospects for assessing functional state mitochondria as a fine indicator course diseases. Results. data domestic foreign sources on parameters functioning in normal pathology were analyzed. It has been shown that highly sensitive changes both exogenous endogenous homeostasis. Functional mitochondria, reactive oxygen species, membrane potential, fatty acid composition membranes used diagnostic prognostic criteria presented indicate need further studies pathology.
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ژورنال
عنوان ژورنال: ????????? ?????????? ? ????????? ???????
سال: 2022
ISSN: ['1998-5029']
DOI: https://doi.org/10.36604/1998-5029-2022-84-116-126